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master's thesis
Sinteza i biološke aktivnosti imidazolnih soli
2021. urn:nbn:hr:182:265349
Sermek, Nikolina
Josip Juraj Strossmayer University of Osijek
Department of Chemistry
Department of Analytical, Organic and Applied Chemistry

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Sermek, N. (2021). Sinteza i biološke aktivnosti imidazolnih soli (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:182:265349

Sermek, Nikolina. "Sinteza i biološke aktivnosti imidazolnih soli." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2021. https://urn.nsk.hr/urn:nbn:hr:182:265349

Sermek, Nikolina. "Sinteza i biološke aktivnosti imidazolnih soli." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2021. https://urn.nsk.hr/urn:nbn:hr:182:265349

Sermek, N. (2021). 'Sinteza i biološke aktivnosti imidazolnih soli', Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, accessed 19 April 2024, https://urn.nsk.hr/urn:nbn:hr:182:265349

Sermek N. Sinteza i biološke aktivnosti imidazolnih soli [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry; 2021 [cited 2024 April 19] Available at: https://urn.nsk.hr/urn:nbn:hr:182:265349

N. Sermek, "Sinteza i biološke aktivnosti imidazolnih soli", Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, Osijek, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:182:265349

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Metadata
TitleSinteza i biološke aktivnosti imidazolnih soli
Title (english)Synthesis and biological activity of imidazolium salts
AuthorNikolina Sermek
MentorMarija Jozanović (mentor)
Committee memberBerislav Marković (predsjednik povjerenstva)
Committee memberBrunislav Matasović (član povjerenstva)
Committee memberMarija Jozanović (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of Chemistry
(Department of Analytical, Organic and Applied Chemistry)
Osijek
Defense date and country2021-12-21, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Analytic Chemistry
Abstract
Poznata je široka primjena kvaternih amonijevih soli imidazola pa tako i njihova antibakterijska i antifungalna svojstva. Provedene su jednostavne reakcije kvaternizacije imidazola, 1-vinilimidazola i 4-metilimidazola s alkil-halogenidom pri čemu je alkilni lanac (R) varirao između 12 i 20 ugljikovih atoma, a za halogenid (X) je uzet bromid ili jodid. Reakcije su se odvijale u bazičnim uvjetima uz acetonitril kao otapalo, u zatvorenoj inertnoj atmosferi dušika pri 100°C ili na sobnoj temperaturi. Uspješno je sintetizirano deset kvaternih amonijevih soli imidazola. Dobiveni spojevi su izolirani i karakterizirani infracrvenom spektroskopijom (IR) te masenom spektrometrijom (MS). Potencijalna antibakterijska svojstva sintetiziranih spojeva nisu ispitivana u ovome radu.
Abstract (english)
Widespread use of quaternary ammonium salts of imidazole is known, as well as their antibacterial and antifungal properties. Simple quaternization reactions of imidazole, 1-vinylimidazole and 4-methylimidazole with alkyl halide were carried out with the alkyl chain (R) varying between 12 and 20 carbon atoms and the bromide or iodide taken as the halide (X). The reactions were performed under basic conditions with acetonitrile as solvent, under a closed inert nitrogen atmosphere at 100° C or at room temperature. Ten quaternary ammonium salts of imidazole have been successfully synthesized. The obtained compounds were isolated and characterized by infrared spectroscopy and mass spectrometry. The potential antibacterial properties of the synthesized compounds have not been investigated in this paper.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:182:265349
Study programmeTitle: Graduate University Study of Chemistry; research program; specializations in: Research program
Course: Research program
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-08-02 09:01:26