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master's thesis
Pregled bioloških aktivnosti kvercetina
2021. urn:nbn:hr:182:493982
Mirosavljević, Marija
Josip Juraj Strossmayer University of Osijek
Department of Chemistry
Department of Analytical, Organic and Applied Chemistry

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Mirosavljević, M. (2021). Pregled bioloških aktivnosti kvercetina (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:182:493982

Mirosavljević, Marija. "Pregled bioloških aktivnosti kvercetina." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2021. https://urn.nsk.hr/urn:nbn:hr:182:493982

Mirosavljević, Marija. "Pregled bioloških aktivnosti kvercetina." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2021. https://urn.nsk.hr/urn:nbn:hr:182:493982

Mirosavljević, M. (2021). 'Pregled bioloških aktivnosti kvercetina', Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, accessed 26 April 2024, https://urn.nsk.hr/urn:nbn:hr:182:493982

Mirosavljević M. Pregled bioloških aktivnosti kvercetina [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry; 2021 [cited 2024 April 26] Available at: https://urn.nsk.hr/urn:nbn:hr:182:493982

M. Mirosavljević, "Pregled bioloških aktivnosti kvercetina", Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, Osijek, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:182:493982

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Metadata
TitlePregled bioloških aktivnosti kvercetina
Title (english)Review of biological activities of quercetin
AuthorMarija Mirosavljević
MentorAna Amić (mentor)
Committee memberOlivera Galović (predsjednik povjerenstva)
Committee memberAna Amić (član povjerenstva)
Committee memberAnamarija Stanković (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of Chemistry
(Department of Analytical, Organic and Applied Chemistry)
Osijek
Defense date and country2021-10-01, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Applied Chemistry
Abstract
Kvercetin (2-(3,4-dihidroksifenil)-3,5,7-trihidroksikromen-4-on) je flavonoid koji je u prirodi prisutan u mnogim biljkama u obliku glikozida. Glavne skupine derivata kvercetina su kvercetin Oglikozidi, a najčešće mjesto glikolizacije nalazi se na C3. Cilj rada je detaljno predstaviti osnovne informacije o kvercetinu; njegovu strukturu i svojstva, biokemiju i sintezu, biodostupnost te metabolizam. Analizirane su znanstvene studije koje istraţuju bioaktivnost kvercetina te je dan sistematski uvid u značaj i utjecaj prehrane bogate kvercetinom na zdravlje, kao i interakcije kvercetina s lijekovima i njegova potencijalna toksičnost. Kvercetin se smatra snaţnim antioksidansom s izraţenom sposobnosti uklanjanja slobodnih radikala i keliranja prijelaznih metalnih iona. Osim antioksidacijskih, kvercetin posjeduje i antivirusna, antikancerogena, protuupalna i brojna druga farmakološki značajna svojstva koja su detaljnije objašnjena u radu. U radu su usporeĎeni rezultati znanstvenih studija koje ispituju oprečno djelovanje kvercetina, a analizirana istraţivanja su pokazala da je kvercetin, ovisno o dozi, potencijalno sredstvo za prevenciju i liječenje raznih bolesti, kao što su neurodegenerativne i kardovaskularne bolesti te mnoge druge.
Abstract (english)
Quercetin (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-H-1-benzopyran-4-one) is a flavonoid present in the plant kingdom in the glycoside form. Main group of quercetin derivates are quercetin O-glycosides, and the main place where glycosylation occurs is C3. The aim of the thesis was to present in details main information regarding quercetin structure and properties, biochemistry and synthesis, bioavailability and metabolism. Scientific studies on quercetin bioactivity were analysed and an insight on the importance and impact of a diet rich in quercetin on health was given, interactions of quercetin with medication and its potential toxic effect were also discussed. Quercetin is considered as a powerful antioxidant with a pronounced capability of free radical elimination and chelation of metals. Aside from antioxidant, quercetin also possesses antiviral, anticancer, anti-inflammatory and other pharmacologically significant properties that were also discussed in the thesis. Results of scientific studies that deal with opposed activity of quercetin were also analysed, and they showed that, depending on the dosage, quercetin is a potential remedy for the prevention and treatment of various illnesses, such as neurodegenerative and cardiovascular and many other.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:182:493982
Study programmeTitle: Graduate University Study of Chemistry; research program; specializations in: Research program
Course: Research program
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-08-03 07:50:42