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undergraduate thesis
Peroksidikacija lipida: metode mjerenja
2018. urn:nbn:hr:182:638777
Boršćak, Denis
Josip Juraj Strossmayer University of Osijek
Department of Chemistry
Department of Analytical, Organic and Applied Chemistry

Cite this document

Boršćak, D. (2018). Peroksidikacija lipida: metode mjerenja (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:182:638777

Boršćak, Denis. "Peroksidikacija lipida: metode mjerenja." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:182:638777

Boršćak, Denis. "Peroksidikacija lipida: metode mjerenja." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:182:638777

Boršćak, D. (2018). 'Peroksidikacija lipida: metode mjerenja', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, accessed 30 December 2024, https://urn.nsk.hr/urn:nbn:hr:182:638777

Boršćak D. Peroksidikacija lipida: metode mjerenja [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry; 2018 [cited 2024 December 30] Available at: https://urn.nsk.hr/urn:nbn:hr:182:638777

D. Boršćak, "Peroksidikacija lipida: metode mjerenja", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, Osijek, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:182:638777

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Metadata
TitlePeroksidikacija lipida: metode mjerenja
Title (english)Peroxidation of lipids: measurement methods
AuthorDenis Boršćak
MentorMirela Samardžić (mentor)
GranterJosip Juraj Strossmayer University of Osijek
Department of Chemistry
(Department of Analytical, Organic and Applied Chemistry)
Osijek
Defense date and country2018-09-10, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Analytic Chemistry
Abstract
Lipidi su prirodni spojevi koji su topivi u organskim otapalima i pripadaju u skupinu estera. Grade ih zasićene ili nezasićene prirodne masne kiseline koje se sastoje od dugačkog ugljikovodičnog lanca koji sadrži paran broj ugljikovih atoma od C14 do C24. Višestruko nezasićene masne kiseline (PUFA) i monozasićene masne kiseline imaju ciskonfiguraciju dvostruke veze. Složeni lipidi su fosfolipidi i sfingolipidi koji sadrže šećere, dušične baze, alkohole i dugolančane masne kiseline. Lipidna peroksidacija je spontani proces koji uzrokuje hidroksilni radikal (OH) i sastoji se od tri faze: inicijacije, propagacije i terminacije. Produkti lipidne peroksidacije nisu stabilni i uzrokuju različite biološke efekte. Fe(II) ion je najznačajniji inicijator peroksidacije koja se odvija mehanizmom slobodnih radikala. Procesi oksidacije lipida prate se različitim metodama i mjernim tehnikama. Spektrofotometrijsko mjerenje konjugiranih UV diena jedna je od izravnih metoda određivanja hidroperoksida. Feritiocijanatna metoda je metoda kojom se određuju hidroperoksidi lipida. Specifične funkcionalne skupine i geometrijska izomerizacija masnih kiselina može se odrediti IR spektroskopijom. Lipidni peroksidi stvaraju mnogobrojne razgradne produkte: aldehide, ugljikovodike, ketone, epokside i aktivne radikale pod djelovanjem iona bakra ili željeza.
Abstract (english)
Lipids are natural compounds which are soluble in organic solvents and they are esters. Lipids are made of saturated or unsaturated natural fatty acids which are made of long hydrocarbon chain with even number of carbon atoms (C14 - C24). Polyunsaturated fatty acids (PUFA) and monosaturated fatty acids have cis-configuration of double bond. Complex lipids are phospholipids and sphingolipids made of sugar, nitrogen base, alcohol and long chains of fatty acids. Lipid peroxidation is spontaneous process caused by OHradical. It consists of three steps: initiation, propagation and termination. Lipid peroxidation products are not stable and cause different biological effects. Fe(II) ion is most important initiator of peroxidation which is made by free radical mechanism. Processes of lipid oxidation are being studied with different methods and measurement techniques. Spectrophotometric measurement of conjugated UV diens is one of direct methods for hydroperoxides determination. The ferricthiocyanate method is method for estimation of lipid hydroperoxides. Specifics functional groups and geometrical isomerization of fatty acids can be determined with IR spectroscopy. Lipid peroxides, under the influence of copper and iron ions, create many products: aldehydes, hydrocarbons, ketones, epoxides and active radicals.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:182:638777
Study programmeTitle: Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije)
Type of resourceText
File originBorn digital
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Created on2018-12-17 11:41:29