Atmospheric pollutants in the boundary layer of the atmosphere have a major impact on life on the Earth in general, which includes health effects, effects on a certain plant species and durability of some materials. Ozone is one of the most significant pollutants in urban areas formed through many reactions as a secondary pollutant from primary pollutants (volatile organic compounds or nitrogen oxides) that directly occur in atmosphere through emission. Results of measurements of the ozone and atmospheric microconstituents (nitrogen dioxide, sulphur dioxide, carbon monoxide, benzene and PM10) volumes for the 2012th The principal components analysis was also used to analyze nitrogen dioxide, sulphur dioxide, carbon monoxide, benzene and PM growth season in Osijek are presented in this thesis. Monitoring station for the ozone sampling was placed in the northern part of the town (Tvrđa) along the Drava river at an altitude of about 4 m above the ground. Because of such position, it was easy to determine possible influences of the northern (rural and marshy) and southern (urban, industrial) parts of the town as two different types of air masses. The low values of measured ozone is indicating that the air is well mixed. Factor analysis was used to compare the values of measured ozone with the values of pollutants and meteorological effects obtained from the automatic monitoring station and to indicate its possible interdependence. The principal components analysis showed that ozone was in positive correlation with temperature. 10 concentrations and meteorological parameters also for determination of a certain interdependence. There are three major factors that are shown and the total variance was 56,44 %. It was noticed that there is a positive correlation between nitrogen oxide and PM10, and between carbon monoxide, benzene and sulphur dioxide. Ozone concentrations correlated negatively with all the other measured pollutants.