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master's thesis
Nova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide
2022. urn:nbn:hr:182:510240
Tot, Dora
Josip Juraj Strossmayer University of Osijek
Department of Chemistry
Department of Analytical, Organic and Applied Chemistry

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Tot, D. (2022). Nova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:182:510240

Tot, Dora. "Nova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:182:510240

Tot, Dora. "Nova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:182:510240

Tot, D. (2022). 'Nova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide', Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:182:510240

Tot D. Nova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry; 2022 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:182:510240

D. Tot, "Nova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide", Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, Osijek, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:182:510240

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Metadata
TitleNova kvarterna amonijeva sol kao antimikrobni agens i aktivna komponenta potenciometrijskog senzora za tenzide
Title (english)New quaternary ammonium salt as an antimicrobial agent and an active ingredient of hte potentiometric sensor for tenzides
AuthorDora Tot
MentorMarija Jozanović (mentor)
MentorNikola Sakač (komentor)
Committee memberAleksandar Sečenji (predsjednik povjerenstva)
Committee memberMarija Jozanović (član povjerenstva)
Committee memberMartina Šrajer Gajdošik (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of Chemistry
(Department of Analytical, Organic and Applied Chemistry)
Osijek
Defense date and country2022-10-25, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Organic Chemistry
Abstract
Nova kvarterna amonijeva sol (QAC) - kationski tenzid 2-metil-1,3-dioktadecil-benzo[d]imidazol (MDBI) korišten je kao protu-ion u ionoforu za izradu i testiranje potenciometrijskog senzora za tenzide i kao antimikrobni agens. Kationski tenzidi često imaju antimikrobna svojstva i primjenjuju se kao antiseptici i dezinficijensi. Najnoviji primjer su dezinficijensi za suzbijanje širenja SARS-CoV-2 virusa na bazi QAC-ova ili alkohola. Ionofor za senzor za tenzide na bazi PVC tekuće mambrane bio je MDBI s terefenilborat (TPB) protu-ionom. Senzor je uspješno izrađen i okarakteriziran te testiran na modelnim sustavima i realnim sustavima otpadnih voda i komercijalnih proizvoda. Antimikrobno djelovanje MDBI uspoređeno je s komercijalnim sredstvom za čišćenje kupaonica koji sadrži kationski tenzid (Cilit BANG®) na 5 sojeva mikroorganizama gdje je kao hranjiva podloga za bakterije korišten Mueller – Hinton agar, a za kvasce i plijesni Sabouraud agar. Ispitivani mikroorganizmi su: Pseudomonas aeruginosa, Staphylococcus aureus, Aspergillus niger, Escherichia coli te Candida albicans. Izmjerene su njihove zone inhibicije. Usporedbom zona inhibicije za MDBI i Cilit BANG®, MDBI je pokazao superiornost u inhibiciji Pseudomonas aeruginosa koji je rezistentan na uobičajne antimikrobne agense.
Abstract (english)
A new quaternary ammonium salt (QAC) - cationic surfactant 2-methyl-1,3-dioctadecyl-benzo[d]imidazole (MDBI) was used as a counterion in an ionophore for making and testing a potentiometric sensor for surfactants and as an antimicrobial agent. Cationic surfactants often have antimicrobial properties so they are used as antiseptics and disinfectants. The most recent example are disinfectants based on QACs or alcohol which are used for controlling the spread of the SARS-CoV-2 virus. The ionophore for the surfactant sensor based on PVC liquid membrane was MDBI with terephenylborate (TPB) as the counterion. The sensor was successfully manufactured, characterized, and tested on model systems, real wastewater systems, and commercial products. The antimicrobial activity of MDBI was tested and compared with a commercial bathroom cleaner containing a cationic surfactant (Cilit BANG®) on 5 strains of microorganisms, where Mueller-Hinton agar was used as a growth medium for bacteria, and Sabouraud agar was used for yeasts and molds. The observed microorganisms were: Pseudomonas aeruginosa, Staphylococcus aureus, Aspergillus niger, Escherichia coli, and Candida albicans. Their zones of inhibition were measured. By comparing the zones of inhibition for MDBI and Cilit BANG®, MDBI showed superiority in the inhibition of Pseudomonas aeruginosa, which is resistant to common antimicrobial agents.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:182:510240
Study programmeTitle: Graduate University Study of Chemistry; research program; specializations in: Research program
Course: Research program
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-11-02 10:44:54