Single crystal, otherwise known as a monocrystal, is a crystalline solid that has a regular three-dimensional structure. The perfect single crystals are transparent, sharp corners and with measurements from 0.1 to 0.4 mm. Due to their regular and uninterrupted internal structure, they contain outstanding properties such as electrical, optical, thermal and many others. This paper describes single crystal preparative methods from a solution such as slow-cooling method, solvent evaporation, solvent diffusion and vapour difussion. Single crystals can also be grown by melt methods, Czohralski process and Bridgman technique, and sublimation methods. The experimental part describes the procedure for determining the solubility of individual alcohol compounds in different solvents and the choice of solvent-based preparation methods. General crystallographic data of each compound were obtained by X-ray diffraction and it was found that the compound Do6OH crystallizes in two crystal systems. In two different solvents, DMF and DMSO, using the solvent diffusion method, the resulting single crystals crystallize in a orthorhombic and monoclinic crystal system. Single crystals of the compound Do3OH were prepared by the evaporation method from benzene, while the single crystals of the compound Do5OH were prepared by the method of slow cooling from benzene.